Endoplasmin

BE0001165ProteinHumansHSP90B1

ATP-dependent chaperone involved in the processing of proteins in the endoplasmic reticulum, regulating their transport (PubMed:23572575, PubMed:39509507). It is acted on by 10 drugs in DrugBank.

Gene name
HSP90B1
UniProtKB entry
P14625Swiss-Prot
Cellular location
Endoplasmic reticulum lumen
Residues / weight
803 residues · 92,468 Da
Also known as
3.6.4.- · 94 kDa glucose-regulated protein · gp96 homolog · GRP-94 · GRP94

Resolves to

Protein
UniProtP14625UniProt nameENPL_HUMAN
Gene
HGNCHGNC:12028NCBI Gene7184GenBank553797GeneCardsHSP90B1
Pharmacology
IUPHAR/GtoPdb2904KEGGhsa:7184
Structure
PDB4NH9PDB7ULLPDB9N9J
Drugs

What you can answer from here — as of September 07, 2019

10DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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31GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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35+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Endoplasmin, how selective are they, and which programs against it are still in active trials?

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