RAC-beta serine/threonine-protein kinase

BE0001172ProteinHumansAKT2

Serine/threonine kinase closely related to AKT1 and AKT3. It is acted on by 8 drugs in DrugBank.

Gene name
AKT2
UniProtKB entry
P31751Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
481 residues · 55,768 Da
Also known as
2.7.11.1 · PKB beta · Protein kinase Akt-2 · Protein kinase B beta · RAC protein kinase beta

Resolves to

Protein
UniProtP31751UniProt nameAKT2_HUMAN
Gene
HGNCHGNC:392NCBI Gene208GenBank337491GeneCardsAKT2
Pharmacology
IUPHAR/GtoPdb1480KEGGhsa:208
Structure
PDB1GZKPDB1GZNPDB1GZO
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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14Clinical trialsTrials of drugs acting on it, by phase and status
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21GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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49+ReferencesStructured and connected to the statements they support
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Which approved drugs act on RAC-beta serine/threonine-protein kinase, how selective are they, and which programs against it are still in active trials?

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