Cytochrome b5

BE0001173ProteinHumansCYB5A

Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases. It is acted on by 8 drugs in DrugBank.

Gene name
CYB5A
UniProtKB entry
P00167Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
134 residues · 15,330 Da
Also known as
CYB5 · MCB5 · Microsomal cytochrome b5 type A

Resolves to

Protein
UniProtP00167UniProt nameCYB5_HUMAN
Gene
HGNCHGNC:2570NCBI Gene1528GenBank181227GeneCardsCYB5A
Pharmacology
KEGGhsa:1528
Structure
PDB2I96
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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22+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cytochrome b5, how selective are they, and which programs against it are still in active trials?

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