Protein S100-A12

BE0001206ProteinHumansS100A12

S100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It is acted on by 2 drugs in DrugBank.

Gene name
S100A12
UniProtKB entry
P80511Swiss-Prot
Cellular location
Secreted
Residues / weight
92 residues · 10,575 Da
Also known as
CAAF1 · CAGC · Calcium-binding protein in amniotic fluid 1 · Calgranulin-C · CGRP

Resolves to

Protein
UniProtP80511UniProt nameS10AC_HUMAN
Gene
HGNCHGNC:10489NCBI Gene6283GenBank1545946GeneCardsS100A12
Pharmacology
KEGGhsa:6283
Structure
PDB1E8APDB1GQMPDB1ODB
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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20GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Protein S100-A12, how selective are they, and which programs against it are still in active trials?

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