Gag-Pol polyprotein

BE0001210Proteingag-pol

Gag-Pol polyprotein Mediates, with Gag polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic... It is acted on by 8 drugs in DrugBank.

Gene name
gag-pol
UniProtKB entry
P12497Swiss-Prot
Cellular location
Host cell membrane
Residues / weight
1,435 residues · 161,788 Da
Also known as
Pr160Gag-Pol

Resolves to

Protein
UniProtP12497UniProt namePOL_HV1N5
Gene
GenBank328418
Structure
PDB1A43PDB1A8OPDB1AFV
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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24GO termsFunction, process and component, as structured annotations
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10Pfam domainsDomain architecture mapped to Pfam families and clans
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46+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Gag-Pol polyprotein, and which indications are they being tested in?

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