m7GpppX diphosphatase

BE0001215ProteinHumansDCPS

Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. It is acted on by 8 drugs in DrugBank.

Gene name
DCPS
UniProtKB entry
Q96C86Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
337 residues · 38,608 Da
Also known as
3.6.1.59 · DCS-1 · DCS1 · Decapping scavenger enzyme · HINT-5

Resolves to

Protein
UniProtQ96C86UniProt nameDCPS_HUMAN
Gene
HGNCHGNC:29812NCBI Gene28960GenBank21654920GeneCardsDCPS
Pharmacology
KEGGhsa:28960
Structure
PDB1ST0PDB1ST4PDB1XML
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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41+ReferencesStructured and connected to the statements they support
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Which compounds in development act on m7GpppX diphosphatase, and which indications are they being tested in?

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