Thymidylate kinase

BE0001218ProteinMycobacterium tuberculosistmk

Catalyzes the reversible phosphorylation of deoxythymidine monophosphate (dTMP) to deoxythymidine diphosphate (dTDP), using ATP as its preferred phosphoryl donor. It is acted on by 5 drugs in DrugBank.

Gene name
tmk
UniProtKB entry
P9WKE1Swiss-Prot
Residues / weight
214 residues · 22,634 Da
Also known as
2.7.4.9 · dTMP kinase · Thymidine monophosphate kinase · TMPK

Resolves to

Protein
UniProtP9WKE1UniProt nameKTHY_MYCTU
Gene
NCBI Gene888740
Pharmacology
KEGGmtu:Rv3247c
Structure
PDB1G3UPDB1GSIPDB1GTV
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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20+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Thymidylate kinase, and which indications are they being tested in?

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