ATP phosphoribosyltransferase

BE0001228ProteinEscherichia coli (strain K12)hisG

Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). It is acted on by 1 drug in DrugBank.

Gene name
hisG
UniProtKB entry
P60757Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
299 residues · 33,366 Da
Also known as
2.4.2.17 · ATP-PRT

Resolves to

Protein
UniProtP60757UniProt nameHIS1_ECOLI
Gene
NCBI Gene946549GenBank41708
Pharmacology
KEGGecj:JW2001
Structure
PDB1H3DPDB1Q1K
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on ATP phosphoribosyltransferase, and which indications are they being tested in?

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