Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

BE0001242ProteinHumansB3GAT1

Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. It is acted on by 2 drugs in DrugBank.

Gene name
B3GAT1
UniProtKB entry
Q9P2W7Swiss-Prot
Cellular location
Golgi apparatus membrane
Residues / weight
334 residues · 38,256 Da
Also known as
2.4.1.135 · Beta-1,3-glucuronyltransferase 1 · GlcAT-P · GLCATP · GlcUAT-P

Resolves to

Protein
UniProtQ9P2W7UniProt nameB3GA1_HUMAN
Gene
HGNCHGNC:921NCBI Gene27087GenBank8051678GeneCardsB3GAT1
Pharmacology
KEGGhsa:27087
Structure
PDB1V82PDB1V83PDB1V84
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, and which indications are they being tested in?

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