Adenylate kinase

Details

Name
Adenylate kinase
Kind
protein
Synonyms
  • 2.7.4.3
  • Adenylate monophosphate kinase
  • AK
  • ATP-AMP transphosphorylase
  • ATP:AMP phosphotransferase
Gene Name
adk
UniProtKB Entry
P84139Swiss-Prot
Organism
Sporosarcina globispora
NCBI Taxonomy ID
1459
Amino acid sequence
>lcl|BSEQ0016363|Adenylate kinase
MNIVLMGLPGAGKGTQADRIVEKYGTPHISTGDMFRAAIQEGTELGVKAKSFMDQGALVP
DEVTIGIVRERLSKSDCDNGFLLDGFPRTVPQAEALDQLLADMGRKIEHVLNIQVEKEEL
IARLTGRRICKVCGTSYHLLFNPPQVEGKCDKDGGELYQRADDNPDTVTNRLEVNMNQTA
PLLAFYDSKEVLVNINGQKDIKDVFKDLDVILQGNGQ
Number of residues
217
Molecular Weight
23888.06
Theoretical pI
4.74
GO Classification
Functions
adenylate kinase activity / ATP binding / metal ion binding
Processes
AMP salvage
Components
cytoplasm
General Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
Specific Function
adenylate kinase activity
Pfam Domain Function
Signal Regions
Not Available
Transmembrane Regions
Not Available
Cellular Location
Cytoplasm
Gene sequence
Not Available
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDP84139
UniProtKB Entry NameKAD_SPOGL
PDB ID(s)1S3G
General References
  1. Bae E, Phillips GN Jr: Structures and analysis of highly homologous psychrophilic, mesophilic, and thermophilic adenylate kinases. J Biol Chem. 2004 Jul 2;279(27):28202-8. Epub 2004 Apr 20. [Article]
  2. Gilles AM, Glaser P, Perrier V, Meier A, Longin R, Sebald M, Maignan L, Pistotnik E, Barzu O: Zinc, a structural component of adenylate kinases from gram-positive bacteria. J Bacteriol. 1994 Jan;176(2):520-3. [Article]

Associated Data

Drug Relations
DrugDrug groupPharmacological action?TypeActionsDetails
Bis(Adenosine)-5'-PentaphosphateexperimentalunknowntargetDetails