Triosephosphate isomerase

BE0001256ProteinPlasmodium falciparumTPI

Catalyzes the interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic and gluconeogenic pathways. It is acted on by 6 drugs in DrugBank.

Gene name
TPI
UniProtKB entry
Q07412Swiss-Prot
Residues / weight
248 residues · 27,935 Da
Also known as
5.3.1.1 · PfTIM · TIM · Triose-phosphate isomerase

Resolves to

Protein
UniProtQ07412UniProt nameTPIS_PLAFA
Gene
GenBank160706
Structure
PDB1LYXPDB1LZOPDB1M7O
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Triosephosphate isomerase, and which indications are they being tested in?

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