Ribosomal small subunit pseudouridine synthase A

BE0001276ProteinHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)rsuA

Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA. It is acted on by 1 drug in DrugBank.

Gene name
rsuA
UniProtKB entry
P45124Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
232 residues · 26,212 Da
Also known as
16S pseudouridylate 516 synthase · 16S rRNA pseudouridine(516) synthase · 5.4.99.19 · rRNA pseudouridylate synthase A · rRNA-uridine isomerase A

Resolves to

Protein
UniProtP45124UniProt nameRSUA_HAEIN
Gene
NCBI Gene950576GenBank1574175
Pharmacology
KEGGhin:HI1243
Structure
PDB1VIO
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Ribosomal small subunit pseudouridine synthase A, and which indications are they being tested in?

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