DNA-binding transcriptional regulator NtrC

BE0001282ProteinSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)glnG

Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. It is acted on by 1 drug in DrugBank.

Gene name
glnG
UniProtKB entry
P41789Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
469 residues · 52,270 Da
Also known as
Nitrogen regulation protein NR(I) · Nitrogen regulator I · NRI · ntrC

Resolves to

Protein
UniProtP41789UniProt nameNTRC_SALTY
Gene
NCBI Gene1255531GenBank728724
Pharmacology
KEGGstm:STM4005
Structure
PDB1DC7PDB1DC8PDB1J56
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on DNA-binding transcriptional regulator NtrC, and which indications are they being tested in?

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