Carboxymethylenebutenolidase

BE0001299ProteinPseudomonas sp. (strain B13)clcD

Ring cleavage of cyclic ester dienelactone to produce maleylacetate. It is acted on by 2 drugs in DrugBank.

Gene name
clcD
UniProtKB entry
P0A115Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
236 residues · 25,555 Da
Also known as
3.1.1.45 · Dienelactone hydrolase · DLH

Resolves to

Protein
UniProtP0A115UniProt nameCLCD_PSEKB
Gene
GenBank151137
Structure
PDB1DINPDB4P93PDB4U2B
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Carboxymethylenebutenolidase, and which indications are they being tested in?

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