Penicillin V acylase

BE0001304ProteinLysinibacillus sphaericus

Catalyzes the hydrolysis of penicillin V to 6-aminopenicillanate (6-APA) (PubMed:30243389, PubMed:3026906, PubMed:9009066). It is acted on by 2 drugs in DrugBank.

UniProtKB entry
P12256Swiss-Prot
Residues / weight
338 residues · 37,457 Da
Also known as
3.5.1.11 · BspPVA · Penicillin acylase · Penicillin amidohydrolase · Penicillin V amidase

Resolves to

Protein
UniProtP12256UniProt namePAC_LYSSH
Gene
GenBank143306
Structure
PDB2IWMPDB2PVAPDB2QUY
Drugs

What you can answer from here — as of May 03, 2025

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Penicillin V acylase, and which indications are they being tested in?

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