Non-secretory ribonuclease

BE0001306ProteinHumansRNASE2

This is a non-secretory ribonuclease. It is acted on by 2 drugs in DrugBank.

Gene name
RNASE2
UniProtKB entry
P10153Swiss-Prot
Cellular location
Lysosome
Residues / weight
161 residues · 18,354 Da
Also known as
4.6.1.18 · EDN · Eosinophil-derived neurotoxin · Ribonuclease 2 · Ribonuclease US

Resolves to

Protein
UniProtP10153UniProt nameRNAS2_HUMAN
Gene
HGNCHGNC:10045NCBI Gene6036GenBank181955GeneCardsRNASE2
Pharmacology
KEGGhsa:6036
Structure
PDB1GQVPDB1HI2PDB1HI3
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Non-secretory ribonuclease, and which indications are they being tested in?

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