Coproporphyrin III ferrochelatase

BE0001307ProteinBacillus subtilis (strain 168)cpfC

Involved in coproporphyrin-dependent heme b biosynthesis (PubMed:25646457, PubMed:25908396). It is acted on by 2 drugs in DrugBank.

Gene name
cpfC
UniProtKB entry
P32396Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
310 residues · 35,348 Da
Also known as
4.99.1.1 · 4.99.1.9 · Ferrochelatase · Heme synthase · hemF

Resolves to

Protein
UniProtP32396UniProt nameCPFC_BACSU
Gene
NCBI Gene939772GenBank143044
Pharmacology
KEGGbsu:BSU10130
Structure
PDB1AK1PDB1C1HPDB1C9E
Drugs

What you can answer from here — as of May 03, 2025

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Coproporphyrin III ferrochelatase, and which indications are they being tested in?

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