Biphenyl-2,3-diol 1,2-dioxygenase

BE0001308ProteinBurkholderia xenovorans (strain LB400)bphC

Shows a preference for catechols with groups immediately adjacent to the hydroxyl substituents. It is acted on by 6 drugs in DrugBank.

Gene name
bphC
UniProtKB entry
P47228Swiss-Prot
Residues / weight
298 residues · 32,471 Da
Also known as
1.13.11.39 · 2,3-dihydroxybiphenyl dioxygenase · 23OHBP oxygenase · DHBD

Resolves to

Protein
UniProtP47228UniProt nameBPHC_PARXL
Gene
GenBank397884
Pharmacology
KEGGbxb:DR64_8614
Structure
PDB1HANPDB1KMYPDB1KND
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
14+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Biphenyl-2,3-diol 1,2-dioxygenase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In