Chloramphenicol acetyltransferase

BE0001320ProteinPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)cat

This enzyme is an effector of chloramphenicol (Cm) resistance in bacteria. It is acted on by 2 drugs in DrugBank.

Gene name
cat
UniProtKB entry
P26841Swiss-Prot
Residues / weight
212 residues · 23,524 Da
Also known as
2.3.1.28 · catB7 · XAT · Xenobiotic acetyltransferase

Resolves to

Protein
UniProtP26841UniProt nameCAT4_PSEAE
Gene
NCBI Gene878374GenBank4104539
Pharmacology
KEGGag:AAD02068
Structure
PDB1XATPDB2XAT
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Chloramphenicol acetyltransferase, how selective are they, and which programs against it are still in active trials?

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