Signal peptidase I

BE0001322ProteinEscherichia coli (strain K12)lepB

Signal peptidase I (Escherichia coli (strain K12)) is a protein target in DrugBank. It is acted on by 3 drugs in DrugBank.

Gene name
lepB
UniProtKB entry
P00803Swiss-Prot
Cellular location
Cell inner membrane
Residues / weight
324 residues · 35,960 Da
Also known as
3.4.21.89 · Leader peptidase I · SPase I

Resolves to

Protein
UniProtP00803UniProt nameLEP_ECOLI
Gene
NCBI Gene947040GenBank146600
Pharmacology
KEGGecj:JW2552
Structure
PDB1B12PDB1KN9PDB1T7D
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Signal peptidase I, and which indications are they being tested in?

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