N-carbamoyl-D-amino acid hydrolase

BE0001323ProteinAgrobacterium sp. (strain KNK712)

The enzyme catalyzes the hydrolysis of N-carbamoyl-D-amino acids to the corresponding which are useful intermediates in the preparation of beta-lactam antibiotics. It is acted on by 3 drugs in DrugBank.

UniProtKB entry
P60327Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
304 residues · 34,285 Da
Also known as
3.5.1.77 · D-N-alpha-carbamilase

Resolves to

Protein
UniProtP60327UniProt nameDCAS_AGRSK
Gene
GenBank37896753
Structure
PDB1ERZPDB1UF4PDB1UF5
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on N-carbamoyl-D-amino acid hydrolase, and which indications are they being tested in?

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