Nicotinate-nucleotide pyrophosphorylase [carboxylating]

BE0001336ProteinMycobacterium tuberculosisnadC

Involved in the catabolism of quinolinic acid (QA). It is acted on by 4 drugs in DrugBank.

Gene name
nadC
UniProtKB entry
P9WJJ7Swiss-Prot
Residues / weight
285 residues · 29,951 Da
Also known as
2.4.2.19 · QAPRTase · Quinolinate phosphoribosyltransferase [decarboxylating]

Resolves to

Protein
UniProtP9WJJ7UniProt nameNADC_MYCTU
Gene
NCBI Gene886281
Pharmacology
KEGGmtu:Rv1596
Structure
PDB1QPNPDB1QPOPDB1QPQ
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Nicotinate-nucleotide pyrophosphorylase [carboxylating], and which indications are they being tested in?

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