Ammonium transporter AmtB

BE0001338ProteinEscherichia coli (strain K12)amtB

Involved in the uptake of ammonium/ammonia (NH(4)(+)/NH(3)) (PubMed:14668330, PubMed:15361618, PubMed:15563598, PubMed:15876187, PubMed:16910683, PubMed:30211659, PubMed:32662768). It is acted on by 3 drugs in DrugBank.

Gene name
amtB
UniProtKB entry
P69681Swiss-Prot
Cellular location
Cell inner membrane
Residues / weight
428 residues · 44,514 Da
Also known as
Ammonia channel · Ammonia channel AmtB · Ammonia transporter · Ammonium channel AmtB · ybaG

Resolves to

Protein
UniProtP69681UniProt nameAMTB_ECOLI
Gene
NCBI Gene945084GenBank1103924
Pharmacology
KEGGecj:JW0441
Structure
PDB1U77PDB1U7CPDB1U7G
Drugs

What you can answer from here — as of May 03, 2025

3DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Ammonium transporter AmtB, how selective are they, and which programs against it are still in active trials?

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