Nicotinate-nucleotide pyrophosphorylase [carboxylating]

BE0001347ProteinSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)nadC

Involved in the catabolism of quinolinic acid (QA). It is acted on by 1 drug in DrugBank.

Gene name
nadC
UniProtKB entry
P30012Swiss-Prot
Residues / weight
297 residues · 32,560 Da
Also known as
2.4.2.19 · QAPRTase · Quinolinate phosphoribosyltransferase [decarboxylating]

Resolves to

Protein
UniProtP30012UniProt nameNADC_SALTY
Gene
NCBI Gene1251663GenBank415621
Pharmacology
KEGGstm:STM0145
Structure
PDB1QAP
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Nicotinate-nucleotide pyrophosphorylase [carboxylating], and which indications are they being tested in?

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