1-aminocyclopropane-1-carboxylate deaminase
BE0001378ProteinPseudomonas sp. (strain ACP)acdS
Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. It is acted on by 6 drugs in DrugBank.
- Gene name
- acdS
- UniProtKB entry
- Q00740Swiss-Prot
- Cellular location
- Cytoplasmic
- Residues / weight
- 338 residues · 36,672 Da
- Also known as
- 3.5.99.7 · ACC deaminase
Resolves to
Gene
Drugs
What you can answer from here — as of September 07, 2019
Which compounds in development act on 1-aminocyclopropane-1-carboxylate deaminase, and which indications are they being tested in?
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