2-dehydro-3-deoxyphosphooctonate aldolase

BE0001394ProteinShigella flexnerikdsA

2-dehydro-3-deoxyphosphooctonate aldolase (Shigella flexneri) is a protein target in DrugBank. It is acted on by 4 drugs in DrugBank.

Gene name
kdsA
UniProtKB entry
P0A716Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
284 residues · 30,832 Da
Also known as
2.5.1.55 · 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase · KDO 8-P synthase · KDO-8-phosphate synthase · KDOPS

Resolves to

Protein
UniProtP0A716UniProt nameKDSA_SHIFL
Gene
NCBI Gene1024177GenBank24051519
Pharmacology
KEGGsfl:SF1218
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 2-dehydro-3-deoxyphosphooctonate aldolase, and which indications are they being tested in?

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