Urocanate hydratase

BE0001420ProteinPseudomonas putida (strain KT2440)hutU

Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate. It is acted on by 1 drug in DrugBank.

Gene name
hutU
UniProtKB entry
Q88CZ6Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
557 residues · 60,717 Da
Also known as
4.2.1.49 · Imidazolonepropionate hydrolase · Urocanase

Resolves to

Protein
UniProtQ88CZ6UniProt nameHUTU_PSEPK
Gene
NCBI Gene1042837GenBank24986811
Pharmacology
KEGGppu:PP_5033
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Urocanate hydratase, and which indications are they being tested in?

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