V-type sodium ATPase subunit K

BE0001440ProteinEnterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258)ntpK

Involved in ATP-driven sodium extrusion. It is acted on by 2 drugs in DrugBank.

Gene name
ntpK
UniProtKB entry
P43457Swiss-Prot
Cellular location
Cell membrane
Residues / weight
156 residues · 16,037 Da
Also known as
Na(+)-translocating ATPase subunit K · ntpN · Sodium ATPase proteolipid component

Resolves to

Protein
UniProtP43457UniProt nameNTPK_ENTHA
Gene
NCBI Gene13177589GenBank416405
Pharmacology
KEGGehr:EHR_08240
Structure
PDB2BL2PDB2CYDPDB2DB4
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on V-type sodium ATPase subunit K, and which indications are they being tested in?

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