Anaerobic ribonucleoside-triphosphate reductase

BE0001442ProteinEnterobacteria phage T4nrdD

Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. It is acted on by 4 drugs in DrugBank.

Gene name
nrdD
UniProtKB entry
P07071Swiss-Prot
Residues / weight
605 residues · 67,956 Da
Also known as
1.1.98.6 · 1.17.4.2 · 49.1 · 55.11/55.13 · Class III ribonucleoside-triphosphate reductase

Resolves to

Protein
UniProtP07071UniProt nameNRDD_BPT4
Gene
NCBI Gene1258655GenBank1177560
Pharmacology
KEGGvg:1258655
Structure
PDB1H78PDB1H79PDB1H7A
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Anaerobic ribonucleoside-triphosphate reductase, and which indications are they being tested in?

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