Shikimate dehydrogenase (NADP(+))

BE0001445ProteinHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)aroE

Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. It is acted on by 1 drug in DrugBank.

Gene name
aroE
UniProtKB entry
P43876Swiss-Prot
Residues / weight
272 residues · 29,760 Da
Also known as
1.1.1.25 · SDH

Resolves to

Protein
UniProtP43876UniProt nameAROE_HAEIN
Gene
NCBI Gene949697GenBank1573653
Pharmacology
KEGGhin:HI0655
Structure
PDB1P74PDB1P77
Drugs

What you can answer from here — as of September 04, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Shikimate dehydrogenase (NADP(+)), and which indications are they being tested in?

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