RNA-directed RNA polymerase

BE0001453ProteinPseudomonas phage phi6P2

Rna-dependent RNA polymerase part of the packaging complex that packages the viral RNA segments, replicate them into a double-stranded form and transcribe them. It is acted on by 1 drug in DrugBank.

Gene name
P2
UniProtKB entry
P11124Swiss-Prot
Cellular location
Virion
Residues / weight
665 residues · 74,922 Da
Also known as
2.7.7.48 · Protein P2

Resolves to

Protein
UniProtP11124UniProt nameRDRP_BPPH6
Gene
NCBI Gene956436GenBank215481
Pharmacology
KEGGvg:956436
Structure
PDB1HHSPDB1HHTPDB1HI0
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on RNA-directed RNA polymerase, and which indications are they being tested in?

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