UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

BE0001454ProteinEscherichia coli (strain K12)murG

Cell wall formation (PubMed:1649817). It is acted on by 2 drugs in DrugBank.

Gene name
murG
UniProtKB entry
P17443Swiss-Prot
Cellular location
Cell inner membrane
Residues / weight
355 residues · 37,814 Da
Also known as
2.4.1.227 · Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Resolves to

Protein
UniProtP17443UniProt nameMURG_ECOLI
Gene
NCBI Gene946321GenBank809684
Pharmacology
KEGGecj:JW0088
Structure
PDB1F0KPDB1NLM
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, and which indications are they being tested in?

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