Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase

BE0001455ProteinSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)thiD

Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. It is acted on by 1 drug in DrugBank.

Gene name
thiD
UniProtKB entry
P55882Swiss-Prot
Residues / weight
266 residues · 28,543 Da
Also known as
2.7.1.49 · HMP kinase · HMP-P kinase · HMP-phosphate kinase · HMPP kinase

Resolves to

Protein
UniProtP55882UniProt nameTHID_SALTY
Gene
NCBI Gene1253667GenBank1842117
Pharmacology
KEGGstm:STM2146
Structure
PDB1JXHPDB1JXIPDB1LLJ
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase, and which indications are they being tested in?

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