Glucose-6-phosphate isomerase B
Details
- Name
- Glucose-6-phosphate isomerase B
- Kind
- protein
- Synonyms
- 5.3.1.9
- GPI B
- PGI-B
- PHI-B
- Phosphoglucose isomerase B
- Phosphohexose isomerase B
- Gene Name
- pgiB
- UniProtKB Entry
- P13376Swiss-Prot
- Organism
- Geobacillus stearothermophilus
- NCBI Taxonomy ID
- 1422
- Amino acid sequence
>lcl|BSEQ0019125|Glucose-6-phosphate isomerase B MAISFDYSNALPFMQENELDYLSEFVKAAHHMLHERKGPGSDFLGWVDWPIRYDKNEFSR IKQAAERIRNHSDALVVIGIGGSYLGARAAIEALSHTFHNQMNDTTQIYFAGQNISSTYI SHLLDVLEGKDLSINVISKSGTTTEPAIAFRIFRDYMEKKYGKEEARKRIYVTTDRTKGA LKKLADQEGYETFVIPDNIGGRYSVLTAVGLLPIAVAGLNIDRMMEGAASAYHKYNNPDL LTNESYQYAAVRNILYRKGKAIELLVNYEPSLHYVSEWWKQLFGESEGKDQKGLFPASVD FTTDLHSMGQYVQEGRRNLIETVLHVKKPQIELTIQEDPENIDGLNFLAGKTLDEVNKKA FQGTLLAHVDGGVPNLIVELDEMNEYTFGEMVYFFEKACGISGHLLGVNPFDQPGVEAYK KNMFALLGKPGFEDEKAALMKRLSK
- Number of residues
- 445
- Molecular Weight
- 50140.56
- Theoretical pI
- 5.93
- GO Classification
- Functionsglucose-6-phosphate isomerase activityProcessesgluconeogenesis / glycolytic processComponentscytoplasm
- General Function
- Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
- Specific Function
- carbohydrate derivative binding
- Pfam Domain Function
- PGI (PF00342)
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0002915|1338 bp ATGGCTATCTCTTTTGATTACTCTAATGCATTACCATTTATGCAAGAGAATGAACTAGAT TATTTAAGCGAATTTGTAAAAGCAGCTCATCATATGCTTCATGAAAGGAAAGGTCCAGGA TCGGATTTTCTCGGTTGGGTTGATTGGCCGATCCGCTATGATAAAAACGAATTTTCGCGA ATCAAACAAGCTGCTGAAAGAATCCGGAATCATTCAGACGCTCTTGTGGTGATCGGCATT GGCGGATCTTATTTGGGTGCAAGGGCGGCTATTGAAGCATTATCCCATACCTTTCATAAC CAAATGAACGATACGACACAAATTTATTTTGCTGGTCAGAATATCAGTTCTACTTATATC TCTCATTTATTAGATGTATTAGAAGGCAAAGATCTGTCTATCAATGTCATTTCTAAATCG GGAACAACGACAGAGCCTGCCATTGCTTTCCGCATTTTCCGTGATTACATGGAGAAGAAA TATGGAAAAGAGGAAGCAAGAAAACGGATTTACGTTACTACTGACCGAACAAAAGGAGCA TTAAAAAAGCTCGCCGATCAAGAAGGATATGAAACGTTCGTTATTCCGGATAACATAGGC GGGAGATATTCTGTGCTGACAGCAGTTGGGCTATTACCAATCGCTGTAGCTGGACTGAAT ATTGACCGAATGATGGAAGGGGCAGCATCAGCATATCATAAATATAATAATCCCGATCTT TTAACCAATGAGAGTTATCAGTATGCCGCTGTACGAAATATTCTCTACCGTAAAGGCAAA GCGATCGAATTATTGGTTAATTATGAGCCATCCCTTCATTATGTATCGGAGTGGTGGAAA CAGCTGTTTGGAGAAAGTGAAGGGAAAGATCAGAAAGGACTCTTTCCTGCATCCGTTGAC TTTACAACAGATTTACATTCCATGGGGCAATACGTTCAGGAAGGCCGACGCAATCTGATC GAAACAGTGCTGCATGTCAAGAAACCGCAAATCGAACTGACGATTCAAGAAGATCCAGAA AATATCGATGGATTGAATTTCTTGGCCGGTAAAACGCTGGATGAAGTAAACAAAAAGGCT TTTCAAGGCACGCTATTAGCACATGTAGACGGTGGAGTGCCTAACTTAATTGTTGAACTG GATGAAATGAATGAATACACCTTTGGTGAAATGGTATACTTCTTCGAAAAAGCTTGCGGC ATCAGCGGTCATTTACTCGGTGTGAATCCGTTTGATCAGCCGGGAGTGGAAGCATACAAG AAAAATATGTTTGCCTTACTTGGCAAACCGGGTTTTGAAGATGAAAAAGCGGCTCTCATG AAACGGTTATCTAAATAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P13376 UniProtKB Entry Name G6PIB_GEOSE GenBank Protein ID 40048 GenBank Gene ID X16640 PDB ID(s) 1B0Z, 1C7Q, 1C7R, 2PGI - General References
- Tao WF, Wang LL, Shen RQ, Sheng ZJ: Complete nucleotide sequences of two phosphoglucoisomerase isozymes from Bacillus stearothermophilus. Nucleic Acids Res. 1989 Dec 11;17(23):10107-8. [Article]
- Sun YJ, Chou CC, Chen WS, Wu RT, Meng M, Hsiao CD: The crystal structure of a multifunctional protein: phosphoglucose isomerase/autocrine motility factor/neuroleukin. Proc Natl Acad Sci U S A. 1999 May 11;96(10):5412-7. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details N-Bromoacetyl-Aminoethyl Phosphate experimental unknown target Details 5-Phosphoarabinonic Acid experimental unknown target Details