Glucose-6-phosphate isomerase 2

BE0001469ProteinGeobacillus stearothermophiluspgi2

Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate. It is acted on by 2 drugs in DrugBank.

Gene name
pgi2
UniProtKB entry
P13376Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
445 residues · 50,141 Da
Also known as
5.3.1.9 · Glucose-6-phosphate isomerase B · GPI 2 · GPI B · PGI 2

Resolves to

Protein
UniProtP13376UniProt nameG6PI2_GEOSE
Gene
GenBank40048
Structure
PDB1B0ZPDB1C7QPDB1C7R
Drugs

What you can answer from here — as of May 03, 2025

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Glucose-6-phosphate isomerase 2, and which indications are they being tested in?

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