Mono-ADP-ribosyltransferase C3

BE0001472ProteinClostridium botulinum D phageC3

ADP-ribosylates eukaryotic Rho and Rac proteins on an asparagine residue. It is acted on by 1 drug in DrugBank.

Gene name
C3
UniProtKB entry
P15879Swiss-Prot
Cellular location
Secreted
Residues / weight
251 residues · 27,841 Da
Also known as
2.4.2.- · Exoenzyme C3

Resolves to

Protein
UniProtP15879UniProt nameARC3_CBDP
Gene
NCBI Gene3773098GenBank505281
Pharmacology
KEGGvg:3773098
Structure
PDB1G24PDB1GZEPDB1GZF
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Mono-ADP-ribosyltransferase C3, and which indications are they being tested in?

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