Peptide deformylase

BE0001475ProteinEscherichia coli (strain K12)def

Removes the formyl group from the N-terminal Met of newly synthesized proteins (PubMed:7896716). It is acted on by 5 drugs in DrugBank.

Gene name
def
UniProtKB entry
P0A6K3Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
169 residues · 19,328 Da
Also known as
3.5.1.88 · fms · PDF · Polypeptide deformylase

Resolves to

Protein
UniProtP0A6K3UniProt nameDEF_ECOLI
Gene
NCBI Gene947780GenBank471304
Pharmacology
KEGGecj:JW3248
Structure
PDB1BS4PDB1BS5PDB1BS6
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
9GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
19+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Peptide deformylase, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In