Genome polyprotein

BE0001478ProteinHepatitis C virus genotype 1b (isolate BK)

Mature core protein Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). It is acted on by 27 drugs in DrugBank.

UniProtKB entry
P26663Swiss-Prot
Cellular location
Host endoplasmic reticulum membrane
Residues / weight
3,010 residues · 327,190 Da
Also known as
3.4.22.- · p23

Resolves to

Protein
UniProtP26663UniProt namePOLG_HCVBK
Gene
GenBank329771
Structure
PDB1A1QPDB1BT7PDB1C2P
Drugs

What you can answer from here — as of September 07, 2019

27DrugsApproved to experimental, with action, bond type and pharmacological action
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43GO termsFunction, process and component, as structured annotations
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15Pfam domainsDomain architecture mapped to Pfam families and clans
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61+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Genome polyprotein, how selective are they, and which programs against it are still in active trials?

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