Peptide deformylase

BE0001486ProteinPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)def

Removes the formyl group from the N-terminal Met of newly synthesized proteins. It is acted on by 3 drugs in DrugBank.

Gene name
def
UniProtKB entry
Q9I7A8Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
168 residues · 19,365 Da
Also known as
3.5.1.88 · PDF · Polypeptide deformylase

Resolves to

Protein
UniProtQ9I7A8UniProt nameDEF_PSEAE
Gene
NCBI Gene879306GenBank9945838
Pharmacology
KEGGpae:PA0019
Structure
PDB1IX1PDB1LRYPDB1N5N
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Peptide deformylase, and which indications are they being tested in?

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