S-ribosylhomocysteine lyase

BE0001497ProteinBacillus subtilis (strain 168)luxS

Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. It is acted on by 4 drugs in DrugBank.

Gene name
luxS
UniProtKB entry
O34667Swiss-Prot
Residues / weight
157 residues · 17,714 Da
Also known as
4.4.1.21 · AI-2 synthesis protein · Autoinducer-2 production protein LuxS · ytjB

Resolves to

Protein
UniProtO34667UniProt nameLUXS_BACSU
Gene
NCBI Gene937106GenBank2293157
Pharmacology
KEGGbsu:BSU30670
Structure
PDB1IE0PDB1J98PDB1JQW
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
13+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on S-ribosylhomocysteine lyase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In