S-adenosylmethionine synthase

BE0001499ProteinShigella flexnerimetK

Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. It is acted on by 3 drugs in DrugBank.

Gene name
metK
UniProtKB entry
P0A820Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
384 residues · 41,951 Da
Also known as
2.5.1.6 · AdoMet synthase · MAT · Methionine adenosyltransferase

Resolves to

Protein
UniProtP0A820UniProt nameMETK_SHIFL
Gene
NCBI Gene1025940GenBank24053342
Pharmacology
KEGGsfl:SF2933
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on S-adenosylmethionine synthase, and which indications are they being tested in?

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