Glycylpeptide N-tetradecanoyltransferase

BE0001502ProteinYeastNMT1

Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. It is acted on by 3 drugs in DrugBank.

Gene name
NMT1
UniProtKB entry
P30418Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
451 residues · 51,877 Da
Also known as
2.3.1.97 · Myristoyl-CoA:protein N-myristoyltransferase · NMT · Peptide N-myristoyltransferase

Resolves to

Protein
UniProtP30418UniProt nameNMT_CANAL
Gene
NCBI Gene3635457GenBank170884
Pharmacology
KEGGcal:CaO19.12111
Structure
PDB1IYKPDB1IYLPDB1NMT
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Glycylpeptide N-tetradecanoyltransferase, and which indications are they being tested in?

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