Phosphatidylinositol transfer protein alpha isoform

BE0001505ProteinHumansPITPNA

Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes (PubMed:10531358, PubMed:14962392, PubMed:15522822, PubMed:18636990, PubMed:22822086). It is acted on by 2 drugs in DrugBank.

Gene name
PITPNA
UniProtKB entry
Q00169Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
270 residues · 31,806 Da
Also known as
PI-TP-alpha · PITPN · PtdIns transfer protein alpha · PtdInsTP alpha

Resolves to

Protein
UniProtQ00169UniProt namePIPNA_HUMAN
Gene
HGNCHGNC:9001NCBI Gene5306GenBank189939GeneCardsPITPNA
Pharmacology
KEGGhsa:5306
Structure
PDB1UW5PDB8PQOPDB9TA5
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Phosphatidylinositol transfer protein alpha isoform, and which indications are they being tested in?

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