UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase

BE0001512ProteinSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)arnB

Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) (PubMed:12429098, PubMed:24460375). It is acted on by 2 drugs in DrugBank.

Gene name
arnB
UniProtKB entry
Q8ZNF3Swiss-Prot
Residues / weight
379 residues · 41,165 Da
Also known as
2.6.1.87 · pbgP · pbgP1 · pmrH · Polymyxin resistance protein PmrH

Resolves to

Protein
UniProtQ8ZNF3UniProt nameARNB_SALTY
Gene
NCBI Gene1253819GenBank2921419
Pharmacology
KEGGstm:STM2297
Structure
PDB1MDOPDB1MDXPDB1MDZ
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, and which indications are they being tested in?

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