dTTP/UTP pyrophosphatase

BE0001527ProteinBacillus subtilis (strain 168)maf

Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. It is acted on by 1 drug in DrugBank.

Gene name
maf
UniProtKB entry
Q02169Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
189 residues · 21,295 Da
Also known as
3.6.1.9 · dTTPase/UTPase · Multicopy associated filamentation protein · Nucleoside triphosphate pyrophosphatase · Nucleotide PPase

Resolves to

Protein
UniProtQ02169UniProt nameNTPPA_BACSU
Gene
NCBI Gene936605GenBank143161
Pharmacology
KEGGbsu:BSU28050
Structure
PDB1EX2PDB1EXCPDB4HEB
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on dTTP/UTP pyrophosphatase, and which indications are they being tested in?

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