NADPH-dependent aldehyde reductase YqhD

BE0001545ProteinEscherichia coli (strain K12)yqhD

NADP-dependent ADH activity. It is acted on by 2 drugs in DrugBank.

Gene name
yqhD
UniProtKB entry
Q46856Swiss-Prot
Residues / weight
387 residues · 42,097 Da
Also known as
1.1.1.- · 1.1.1.2 · Alcohol dehydrogenase YqhD · Alcohol/aldehyde oxidoreductase YqhD · Broad-range ADH

Resolves to

Protein
UniProtQ46856UniProt nameYQHD_ECOLI
Gene
NCBI Gene947493GenBank882539
Pharmacology
KEGGecj:JW2978
Structure
PDB1OJ7PDB4QGS
Drugs

What you can answer from here — as of June 26, 2025

2DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on NADPH-dependent aldehyde reductase YqhD, and which indications are they being tested in?

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