Trans-2,3-dihydro-3-hydroxyanthranilate isomerase

BE0001548ProteinPseudomonas fluorescensphzF

Isomerase that catalyzes the condensation of two molecules of trans-2,3-dihydro-3-hydroxyanthranilic acid (DHHA) into the phenazine ring system. It is acted on by 2 drugs in DrugBank.

Gene name
phzF
UniProtKB entry
Q51792Swiss-Prot
Residues / weight
278 residues · 30,053 Da
Also known as
5.3.3.17 · Phenazine/pyocyanine biosynthesis protein PhzF

Resolves to

Protein
UniProtQ51792UniProt namePHZF_PSEFL
Gene
GenBank1045018
Pharmacology
KEGGag:AAC18905
Structure
PDB1T6KPDB1U1VPDB1U1W
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Trans-2,3-dihydro-3-hydroxyanthranilate isomerase, and which indications are they being tested in?

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