4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

BE0001574ProteinShigella flexneriispE

Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. It is acted on by 2 drugs in DrugBank.

Gene name
ispE
UniProtKB entry
Q83LD8Swiss-Prot
Residues / weight
283 residues · 30,953 Da
Also known as
2.7.1.148 · 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase · CMK

Resolves to

Protein
UniProtQ83LD8UniProt nameISPE_SHIFL
Gene
NCBI Gene1024154GenBank24051512
Pharmacology
KEGGsfl:SF1211
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, and which indications are they being tested in?

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