Kallikrein-6

BE0001586ProteinHumansKLK6

Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. It is acted on by 1 drug in DrugBank.

Gene name
KLK6
UniProtKB entry
Q92876Swiss-Prot
Cellular location
Secreted
Residues / weight
244 residues · 26,856 Da
Also known as
3.4.21.- · Neurosin · Protease M · PRSS18 · PRSS9

Resolves to

Protein
UniProtQ92876UniProt nameKLK6_HUMAN
Gene
HGNCHGNC:6367NCBI Gene5653GenBank1518788GeneCardsKLK6
Pharmacology
IUPHAR/GtoPdb2376KEGGhsa:5653
Structure
PDB1GVLPDB1L2EPDB1LO6
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Kallikrein-6, and which indications are they being tested in?

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