Methylmalonyl-CoA decarboxylase

BE0001595ProteinEscherichia coli (strain K12)scpB

Catalyzes the decarboxylation of (R)-methylmalonyl-CoA to propionyl-CoA. It is acted on by 1 drug in DrugBank.

Gene name
scpB
UniProtKB entry
P52045Swiss-Prot
Residues / weight
261 residues · 29,172 Da
Also known as
4.1.1.- · 4.1.1.41 · mmcD · Transcarboxylase · ygfG

Resolves to

Protein
UniProtP52045UniProt nameSCPB_ECOLI
Gene
NCBI Gene947408GenBank882447
Pharmacology
KEGGecj:JW2886
Structure
PDB1EF8PDB1EF9
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Methylmalonyl-CoA decarboxylase, and which indications are they being tested in?

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