Genome polyprotein

BE0001612ProteinPoliovirus type 1 (strain Mahoney)

Capsid protein VP1 Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3 (PubMed:2994218). It is acted on by 8 drugs in DrugBank.

UniProtKB entry
P03300Swiss-Prot
Cellular location
Virion
Residues / weight
2,209 residues · 246,538 Da
Also known as
3.4.22.29 · P2A

Resolves to

Protein
UniProtP03300UniProt namePOLG_POL1M
Gene
NCBI Gene919920GenBank61253
Pharmacology
KEGGvg:919920
Structure
PDB1AL2PDB1AR6PDB1AR7
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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25GO termsFunction, process and component, as structured annotations
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8Pfam domainsDomain architecture mapped to Pfam families and clans
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62+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Genome polyprotein, and which indications are they being tested in?

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